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Current projects


This proof-of-concept randomized controlled clinical trial explores the safety, feasibility, and preliminary efficacy of psilocybin-enhanced psychotherapy versus treatment-as-usual among military Veterans being treated for methamphetamine use disorder within a residential treatment facility.

Funding: Steven & Alexandra Cohen Foundation; OHSU Foundation; study drug provided by Usona Institute

This proof-of-concept clinical trial is the first to explore the safety and feasibility of MDMA-assisted psychotherapy conducted in a group therapy format. Participants will be military Veterans with PTSD.


We conducted a focus group regarding trauma-related mental health experiences among gender diverse individuals in order to inform a more inclusive approach to the development of MDMA-assisted therapy for this marginalized group. We are enrolling a cohort of transgender and gender diverse Veterans into our MDMA-assisted group therapy study.

Collaborators: OHSU Dept of Psychiatry; OHSU Transgender Health Program; Dr. Bronner's Family Foundation; study drug provided by Lykos Therapeutics

SNaP Lab is a site for this Phase 3, randomized, double-blind, multicenter study to evaluate the efficacy, safety, and tolerability of psilocybin in adults with Major Depressive Disorder (MDD).

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Many patients with chronic pelvic pain are not adequately helped by current treatments or may experience side effects. Emerging evidence suggests that psilocybin is effective in difficult-to-treat pain syndromes, such as migraines or cluster headaches. This study aims to assess the safety and feasibility of a single dose of psilocybin with supportive therapy to treat chronic pelvic pain and will be the first to evaluate psilocybin therapy for this condition. 

Additional Investigators: Lynne Shinto, ND & Jacq Knapp, MD; Funding: OHSU Women’s Health - Circle of Giving 

This proof-of-concept randomized controlled clinical trial evaluates the safety and effectiveness of MDMA-assisted therapy for adults with social anxiety disorder.

Principal Investigator: Jason Luoma, PhD - Portland Psychotherapy Clinic

OPEN is a nascent practice-based research network, designed to assess the safety and equity of psilocybin services in community-based settings and develop a framework for future studies. The OPEN project aims to collect confidential information from licensed psilocybin facilitators and their clients to assess their experience with legal psilocybin services.

Additional Investigators: Alissa Bazinet, PhD; Todd Korthuis, MD, MPH; Jason Luoma, PhD; Adie Rae, PhD
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If you'd like to make a donation to the SNAP Lab, you can click on the "MAKE A GIFT' button here, enter your information, select 'OTHER AREA' under the Area of Giving drop-down menu, and manually enter

"Dr. Christopher Stauffer".

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