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Current projects


This proof-of-concept randomized controlled clinical trial explores the safety, feasibility, and preliminary efficacy of psilocybin-enhanced psychotherapy versus treatment-as-usual among military Veterans being treated for methamphetamine use disorder within a residential treatment facility.

Sponsor: Steven & Alexandra Cohen Foundation; OHSU Foundation; study drug provided by Usona Institute

This proof-of-concept clinical trial is the first to explore the safety and feasibility of MDMA-assisted psychotherapy conducted in a group therapy format. Participants will be military Veterans with PTSD.


We conducted a focus group regarding trauma-related mental health experiences among gender diverse individuals in order to inform a more inclusive approach to the development of MDMA-assisted therapy for this marginalized group. Stay tuned for the development of a multisite clinical trial...

Collaborators: OHSU Dept of Psychiatry; OHSU Transgender Health Program; Encircle; study drug provided by MAPS PBC

This proof-of-concept randomized controlled clinical trial evaluates the safety and effectiveness of MDMA-assisted therapy for adults with social anxiety disorder.

Principal Investigator: Jason Luoma, PhD - Portland Psychotherapy Clinic

OPEN is a nascent practice-based research network, designed to assess the safety and equity of psilocybin services in community-based settings and develop a framework for future studies. The OPEN project aims to collect confidential information from licensed psilocybin facilitators and their clients to assess their experience with legal psilocybin services.

Additional Investigators: Alissa Bazinet, PhD; Todd Korthuis, MD, MPH; Jason Luoma, PhD; Adie Rae, PhD
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